Feb 25, 20212 minSupposedly "silent" mutation with serious consequencesSo-called silent mutations have no effect on the composition of a protein. They are therefore not considered to promote cancer. However,...
Feb 25, 20213 minSuper-Resolution RNA Imaging in Live CellsInnovative method provides new insight into molecular processes involving RNA Ribonucleic acid (RNA) is key to various fundamental...
Feb 22, 20212 minA new piece of the HIV infection puzzle exploredResearchers from EMBL and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei,...
Feb 5, 20213 minEpigenetic reprogramming turns neural stem cells into drivers of childhood brain tumorsDuring embryonic brain development, neural stem cells pass through a series of strictly regulated development phases. A mutation in a...
Feb 4, 20213 minHow blood stem cells maintain their lifelong potential for self-renewalA characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? ...
Jan 27, 20213 minProtein anchors as a newly discovered key molecule in cancer spread and epilepsyCertain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders. ...
Jan 22, 20212 minHow a protein variant could explain resistance to sleeping sickness drugA specific variant of the surface protein VSG of African trypanosomes, the causative agents of sleeping sickness, is associated with...
Jan 12, 20213 minAnticoagulants reduce the number of brain metastases in miceBrain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue. To facilitate this ...
Dec 16, 20203 minNew mechanism of action: A molecule degrades a cancer-promoting protein by gluing it into filaments“Molecular glue degraders” are a new class of cancer drugs, which “glue” cancer growth-promoting proteins directly to the molecular...