European Vaccine Initiative (EVI) seeks to support disease of poverty vaccine candidates that emerge from European laboratories. As well as directly funding the early stage development of vaccine candidates, EVI acts as a force to federate the major EU organisations involved in the design, development, and testing of novel vaccines. EVI also acts as a focal point for EU and global vaccine research and development activities by coordinating numerous externally funded consortia, which are working towards accelerating the development of safe, effective, and affordable vaccines.